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KMID : 1009020180160040497
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Clinical Psychopharmacology and Neuroscience
2018 Volume.16 No. 4 p.497 ~ p.500
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Clinical Usefulness of Aripiprazole Treatment in a Girl with Prader-Willi Syndrome and Psychosis
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Briegel Wolfgang
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Abstract
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Prader-Willi syndrome (PWS) is a quite rare multi-systemic genetic disorder strongly associated with psychiatric illness in adults, especially psychosis. This report presents a 16-year-old female with PWS and symptoms of brief psychotic disorder with a complete resolution of symptoms under aripiprazole medication. However, an exacerbation occurred after aripiprazole reduction. Apart from a weight gain of about 2 kg over the course of two years, no adverse effects could be found. This first report on the use of aripiprazole in a subject with PWS and psychosis suggests that aripiprazole might be a promising treatment approach in this distinct group of patients.
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KEYWORD
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Prader-Willi syndrome, Aripiprazole, Psychosis, Adolescent, Case reports
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